Robbie and Cyrus, if anyone's familiar with their plan, we have had people try that, and it is very interesting. So, that's also exciting that I'm looking forward to. What's really great is, like I said, I have been using one for about a month and a half now. I think it would be a good idea. NSI-189 is a new antidepressant and cognitive booster. I as well did not anticipate-- like you said, people think, “Oh, I don't need to talk to a dietician.” But the communication has just been so-- I mean, I don't know if I can say names. This is due to that peripheral insulin resistance, it's temporary. Melanie Avalon: I love that so much. Essentially what they are trying to prove is that, if you eat a lot of carbohydrates, you're going to increase your insulin sensitivity. A lot of times, especially if you're stimulating ketones, or if you're eating a lot of protein, you might be also stimulating a little glucagon with that. So, instead, a CGM is sort of like a movie of what's going on inside. The third tactic typically, it's really focusing on adding in some carbohydrates, focusing on muscle mass, and then also fasting. Pregnancy, it does put you in a state of mild insulin resistance, where you're not as glucose tolerance as maybe when you weren't pregnant. I've often heard that that's a pretty telling thing that people don't often measure, but you could measure it. I've seen that alone also help bring down those fasting glucose values. Well, the very last question that I ask every single guest on this podcast comes from my growing realization each and every day, just how important mindset is surrounding everything. So, that's something else-- if you see your fasting glucose, rise your insolence in a good level, do a little check and try to assess, “Am I stressed?” “Am I getting out in nature?” “Am I seeing sunlight?” “Am I taking time for self-care?” “Am I sleeping enough?” Both deep sleep and sleep quantity. I'm sure maybe some people's varies more than others. Melanie Avalon: Yeah. Attain radical health, strength, & vitality. So, it basically tells you your glucose values and it tells you, as you enter how much insulin you're taking, so that you can manage your glucose with medications. What I think A1c is useful for is, if it's majorly high, so if your A1c is 10%, there's no amount of anemia that's correcting for that. I think it's really wonderful when those things come together because when you have all of those skills and assets, they can come together to create amazing things like this company, because Kara herself became frustrated with the traditional healthcare system and started the company called Nutrisense, where she is now the Director of Nutrition. Melanie Avalon: I love this so much. By, November 12, 2020 / Kara is the leading authority on the use of continuous glucose monitoring (CGM) technology, particularly in non-diabetics for the purposes of health optimization, disease prevention, and reversing metabolic dysfunction. I would say I don't do a great job of keeping up with my own social media. He then taught at Ohio State University for a dozen years (where he. But that's not what our dietitians are there for you. Melanie Avalon: Do you have thoughts about fructosamine? And it's simple with keto, and I feel good, my energy is awesome, and I don't want to change that.” Well, it might not be worth it, because it's just so unknown. It's probably a natural adaptation. It's not just something you're going to jump to a diet for two weeks and then jump to something else. Kara Collier: That's exactly right. Melanie Avalon: The blood glucose in your blood, and then there's your cells, and there's this fluid around the cells, so does the blood glucose always have to go through the fluid, and then it enters the cell-- like the potential pathway of blood glucose, is the interstitial fluid like a passive ocean around the cell that the blood glucose passes through? How does it work? So, these spikes are actually independent risk factors for cardiovascular disease, which is again, why monitoring glucose is so important, not just to prevent diabetes, but for all these other health conditions that so many people are affected by. One is because as it was probably made clear today, glucose can be confusing, and it can be nuanced. Of course, you could continue to spot check and get it as close as possible. Fructosamine is instead telling you what your average glucose values were in the last two weeks. Restore gut health and integrity, without the use of probiotics. 95. Example of whole fruit versus juice or Steel-Cut oats versus Instant Oats, the effects are pretty dramatic in glucose responses to just the form the food isn't. By, October 22, 2020 / Up-regulate acetylcholine content in the brain, leading to greater mental agility and performance. Sometimes, people have more work to be done than others, but the level of motivation and invigoration that our customers have to just be optimal and take it to the next level is really inspiring. I will put links to all of that in the show notes. If your fasting insulin is 2 or 1.5, because it's been lowering over time, and your fasting glucose is 115, it's much less concerning than the person who has a fasting glucose of 115 and a fasting insulin of 20 or 30, or 100 because that shows me that your body's pumping out insulin, but not responding to it. One is build an app that is geared towards the nondiabetic and the person who wants to understand their data. Everything you said is exactly how I feel. So, there can be reactive or functional, which is typically after a meal. We have a month to month, again, for the commitment-phobic people out there where you could cancel it anytime. This is where all the research associated with elevated fasting glucose values. Melanie Avalon: Listeners, so speaking from my experience, because I didn't know what to expect going into all of this. Ancient herbalism to up-regulate energy levels, in the modern world. Then they were 85, and 95. Let's say you follow ketogenic diet, you like what you're doing, and you just want to see like, where am I glucose levels at? These statements have not been evaluated by the FDA. Friends, I've been using a continuous glucose monitor. For the longer plans, if you know, I have 30 pounds, I want to lose or I'm pre-diabetic, or I know I want to try like a couple different diets and experiment, I think three months is a good option. So, that totally makes sense. A lot of this is related to diet and exercise, and all the things we'll dive in today. The brain is typically sending these messages. It's right there in the app that you can send a message anytime you're confused, and you're always getting feedback from that coach. What's going on there? So, the fructosamine, what is that looking at? Melanie Avalon: So, it's in the context of eating, not the fasting, or it does happen in the fasting as well? This is my review of the brand new Eversense 90 day continuous glucose monitoring system. It's about something that I have been personally experimenting with for the past month and a half or so. Some people see this effect more intensely than others do, so this is something else where I have had clients where just one glass of wine at night causes them to dip in the middle of the night. Melanie Avalon: I'm so excited that you have so much experience with seeing so many people trying different diets and what it does to their levels. So, like hypothyroidism, can also cause hypoglycemia. Another thing we like to really emphasize is making sure you're doing some strength training and making sure you're physically active because in general, the more lean muscle mass you have, the lower your fasting glucose are going to be and the more enhanced glucose tolerance you have. If you were to just go to your doctor's office, and you were going to check and see how your glucose values looked, you would probably get two metrics. Type 1 diabetes is where you don't produce insulin, that's the main market for CGMs. Has beneficial effects on major organs of the body. You can see was my fasting glucose value yesterday higher or lower than today when I made X, Y, Z adjustment? Having that data helps speed up that experimentation process. But that's an option if you thought maybe I want to do a month, and then you could switch plans if you feel you'd like it. Thanks for having me. You're speaking about with the physiological insulin resistance. It’s all about taking our health into our own hands through research, e… So, the first thing we want to look at is how high does your glucose value go? Whereas if you have a glucometer at home, and you're pricking your finger, that's just a snapshot in time. For Exclusive Offers And Discounts, And More On The Science Of Skincare, Get On Melanie's Private Beautycounter Email List At Melanieavalon.com/cleanbeauty! I will say that some people, especially people following a ketogenic diet, or really low carb diet, their glucose might decrease after meals, but it's not this huge spike and drop. You've been dying to hear my official interview and thoughts on the topic. Find Your Perfect Beautycounter Products With Melanie's Quiz: December 24, 2020 / Actually, starting there, with actual-- the CGM, so that listeners can actually know what this device is. I think a CGM could be an alternative because we can see these nuances and your data and get an understanding of if it looks healthy or not. Non-Toxic Beauty Products Tested For Heavy Metals, Which Support Skin Health And Look Amazing! As you mentioned, I am a registered dietitian, and I started my career working in hospitals, particularly ICUs. Kara, thank you so much for being here. I guess there's more there. So, that's my hypothesis is that you're really just burning extra calories, higher basal metabolic rates. If there is a person who is not the type that wants to be keto their whole life and actually does want to eat carbs, practically, how might it look like that they could address that because Gabriella, for example, she said, “How can one get down the blood glucose levels to physiological insulin resistance? And this can feel really, really awful for a lot of people. Melanie Avalon: I love your approach to all of this so much. Unlike the other offers listed here, this one can be used anywhere in the US (except NY), as well as Puerto Rico, Australia, Canada, Hong Kong, Singapore, South Korea, and the United Kingdom. Or is it just a three-month reflection of cells? I want to make sure that we're picking something that is sustainable as well. Melanie Avalon: It's going well. So, you really can only see this with a CGM. If you can see it's off, you want to be able to adjust the values, but the app that comes with the Libre does not allow you to do that. From there, you're usually good to go. Recharge and perform with deep, non-caffeinated energy. I don't want to have a big carb meal every once in a while,” then it's probably not a big deal at all. With that metric, we're really looking for 70 to 90. I've done three FreeStyle Libres now, and I have been checking them against my own blood glucose-- Sorry, everything's [unintelligible [00:15:18] my head, blood glucose monitor. Then, we really want to focus on the trends that the CGM is providing us because that's where infinite insights lie. 140, and then they're back to baseline. Other causes, potential causes of hypoglycemia, especially reactive hypoglycemia is if you're somebody who maybe has hypocortisolism, so lack of glucocorticoids from the adrenal glands can increase glucose oxidation and decrease gluconeogenesis. I think that that really comes out during pregnancy, because you're in this state of physiological insulin resistance. Carbs don't tempt me. A stimulating and wakefulness promoting, nootropic formula. But I read that below six was pretty good for fasting insulin, and mine was 4.5. It's just titrating carbs up, timing it around exercise and see how those overnight values change. So, if it was zero, you probably wouldn't be alive. It's been really, really valuable. I'm just trying to understand this. But if you're okay with three or four days of high numbers, because you're really upping your carbs, all of a sudden, it should reverse fairly quickly at that point. So, people who might be having issues before, or they might have a poor diet, but they kind of got away with it because their system was functioning a little bit more appropriately. She said, “Can the glucose monitor be used during pregnancy to avoid the icky glucose drink? So, if you have one spike to 140, every once in a while, that is no big deal. Kara Collier: It does vary. I'm actually interviewing Levels tomorrow. For anemia, wouldn't they be dying sooner so you might see a lower HbA1c when really--, Melanie Avalon: Of course, in anemia, they might think their A1c is fine, but there actually might be problems because the blood cells are--. Sue, for example, says, can she get a how-to interpret readings. We can all do better by eating more whole foods and avoiding anything processed. And it takes a little bit of experimentation and trial and error. How are they different from blood glucose specifically? : app only support? I would say as a general rule of thumb, it can be pretty quick. Several companies have been working on CGM systems, with the aim of making care easier for those living with the condition. Another timeline question, the FreeStyle Libre and Nutrisense, it's a two-week period, like we've been saying. I've seen what I can learn and I'm starting to see what I have a lot of questions about, but for a little bit about Kara. I am learning so much about my health, about monitoring my diet, about how food and fasting and things like that affect me. One day of bad sleep or some stress, or maybe you've got some adrenaline going on, because you're under pressure or something, and that fasted glucose value could be totally different than it looks the day before. If people are eating fruit and they're taking a lot of digestive enzymes with it, would that potentially make it more sugary then? As FDA said, the CGMs are medical devices, so they regulate them and they say it needs to have a prescription, where something like a glucometer that you're actually drawing some blood from your finger is not a medical device, according to the FDA, so you can buy it over the counter. From there, I really got to think like, “What is the root cause with all of these conditions we're seeing?” It really comes down to metabolic health and insulin resistance. Have you seen trends with that? Learn about our diabetic products including FreeStyle Libre – flash glucose monitoring, FreeStyle Navigator II – continuous glucose monitoring and FreeStyle Optium / Precision Neo - blood glucose and ketone monitoring system. There's absolutely no one size fits all. This one, I'm definitely going to calibrate right after we talk because I'm fasted right now. Kara Collier: Yeah, it can happen in either. These people have elevated insulin levels as well because they have pathological insulin resistance. They're like, “What the heck is going on? Listeners, the show notes for today's episode, there will be a full transcript and we'll put links to everything, that will be at melanieavalon.com/nutrisense. Melanie Avalon: Do you have any idea why with the physiological insulin resistance that occurs on purpose during pregnancy? Mira And Jayson Calton: Bone Health, Micronutrient Deficiencies, Osteoporosis, Multivitamin Problems, Calcium, Vitamin K, Acid/Alkaline Base, Alcohol For Bone Heath, Omega 3s, Osteogenic Loading, And More! They’re more expensive than glucose meters and your insurance or Medicaid might not cover one. So, this is really helpful. 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